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Treatment of gum disease and bone loss with the medicine made from patient blood and artificial bone

A comparative evaluation of A PRF plus and A PRF with alloplast bone graft in the treatment of intrabony defects in chronic periodontitis A split mouth study

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/01/017225
Enrollment
9
Registered
2019-01-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: ADVANCED PRF PLUS WITH ALLOPLAST BONE GRAFT: ADVANCED PRF PLUS IS A BLOOD EXTRACT AND NOT A PHARMACEUTICAL PRODUCT. 10 ML OF BLOOD WILL BE COLLECTED FROM THE ANTECUBITAL VEIN OF THE PAT

Sponsors

ESHA THAKOR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients having moderate to severe periodontitis, patients who are systemically healthy and having more than 6 mm vertical probing depth, having interproximal intrabony defects of more than or equal to 4 mm one on either side of the arch which is radiographically detectable will be included.

Exclusion criteria

Exclusion criteria: Patients who are known case of systemic disease, having abusive habits such as smoking, women who are pregnant or lactating, who are taking anti-inflammatory or antibiotic drugs or has taken within previous 3 months and patients who have done blood transfusion or blood donation in last 6 months will be excluded

Design outcomes

Primary

MeasureTime frame
Radiographic measurements using CBCTTimepoint: BASELINE AND 6 MONTHS

Secondary

MeasureTime frame
Site specific plaque index (PI) modified Sulcus bleeding index (mSBI) Probing depth (PD) from the gingival margin Clinical attachment level (CAL) along with gingival marginal level (GML)Timepoint: BASELINE AND 6 MONTHS

Countries

India

Contacts

Public ContactDR SUBRAYA BHAT

MANIPAL COLLEGE OF DENTAL SCIENCES MANIPAL

subraya.bhat@manipal.edu9632170341

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026