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Comparative study of the safety and therapeutic efficacy of oral steroids (betamethasone) in pulse dose and oral cyclosporine in the treatment of alopecia areata (patchy hair loss).

Comparative study of the safety and therapeutic efficacy of oral cyclosporine and oral betamethasone minipulse therapy in the treatment of alopecia areata.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/01/017202
Enrollment
60
Registered
2019-01-22
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L639- Alopecia areata, unspecified

Interventions

Intervention1: Oral Betamethasone minipulse therapy: Betamethasone oral mini-pulse 0.1mg/kg body wt./dose on two consecutive days per week for 12 weeks Control Intervention1: Oral Cyclosporine: Oral

Sponsors

Shibashis Chatterjee
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients consenting for the study. 2.All the patients presenting with circumscribed patch of hair loss without any signs of inflammation or scarring,of size > 3cm in diameter. 3.Patients who have symptoms of 3 months or more duration. 4.Patients who have not taken any other modalities of treatment in the last 3 months.

Exclusion criteria

Exclusion criteria: 1.Patients who are k/c/o hypertension. 2.Patients with secondary infection. 3.Pregnant and lactating females. 4.Patients with pre-existing renal and liver diseases. 5.Patients with diabetes mellitus. 6.Patients having any Autoimmune disease like SLE, Sjogrenâ??s Syndrome,etc. 7.Patients having contraindications to the drugs used in the study.

Design outcomes

Primary

MeasureTime frame
Safety of the drugsTimepoint: 3 months

Secondary

MeasureTime frame
Therapeutic efficacy of the drugsTimepoint: 3 months

Countries

India

Contacts

Public ContactShibashis Chatterjee

KIMS & PBM Hospital Bhubaneswar

basanti1953@gmail.com9439549249

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026