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A study to analyse the effectiveness of the medications named magnesium and lignocaine in pain control after back surgeries

A prospective randomized double blinded controlled study to evaluate the efficacy of perioperative intravenous magnesium with lignocaine in post operative opioid requirement in patients undergoing elective spine surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/01/017195
Enrollment
50
Registered
2019-01-22
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Magnesium 30mg/kg and Lignocaine 1.5mg/kg: We are intended to study the efficacy of perioperative intravenous magnesium 30mg/kg plus lignocaine 1.5mg/kg with placebo in post operative

Sponsors

MIOT Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. American society of anesthesiologists physical status class I and II 2. Age between 18 to 60 years

Exclusion criteria

Exclusion criteria: 1. Patients undergoing emergency surgery 2. Patients with pre-existing neurological disorders 3. Patients with liver and renal disease 4. Patients with psychiatric illness 5. Patients on antiepileptic medication 6. Patients with history of allergy to magnesium or lignocaine 7. Patients with cardiac conduction abnormality 8. Patients on chronic opioid therapy 9. Patients on calcium channel blockers 10. Patients with ASA III, IV and V status

Design outcomes

Primary

MeasureTime frame
Post operative opioid requirementTimepoint: 1, 2, 3, 4, 5, 6, 8, 10, 12, 16, 20, 24, 28, 32, 36, 40, 44, 48, 52, 56, 60, 64, 68, 72 in Hours—

Secondary

MeasureTime frame
Pain score with respect to visual analogue scale (VAS)Timepoint: 1, 2, 3, 4, 5, 6, 8, 10, 12, 16, 20, 24, 28, 32, 36, 40, 44, 48, 52, 56, 60, 64, 68, 72 in Hours—

Countries

India

Contacts

Public ContactJanakiraman T

MIOT Hospital

drsatva@gmail.com9841038666

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026