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Comparison of drugs for preventing low BP in caesarean deliveries

Comparative study of effect on fetal acid base balance of different vasopressors for treatment of post spinal hypotension in caesarean deliveries

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/01/017159
Enrollment
200
Registered
2019-01-18
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Pregnant patients for Caesarean delivery

Interventions

None listed

Sponsors

Department of Anaesthesiology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Healthy parturients (ASA physical status I and II) posted for elective caesarean delivery under spinal anaesthesia

Exclusion criteria

Exclusion criteria: 1. ASA physical status III and IV 2. Refuse spinal anaesthesia 3. Have history of known drug allergy 4. Any contraindication to spinal anaesthesia (infection at the needle insertion site, spinal deformity, coagulation disorders) 5. Patients in whom spinal anaesthesia is inadequate for conduct of surgery will be excluded from the study 6. Patients with emergent caesarean delivery for fetal distress and obstetric complications like placenta previa, or placental abruption or cord prolapse 7. Patients with hypovolemia due to any cause and systolic blood pressure (SBP) less than 100 mmHg at the time of induction 8. Patients with known fetal abnormality detected antenatally

Design outcomes

Primary

MeasureTime frame
Difference in umbilical arterial acid base balance with the use of different vasopressor used for treating hypotension during spinal anaesthesia in elective caesarean delivery.Timepoint: Immediately after delivery of the baby

Secondary

MeasureTime frame
1. Maternal haemodynamics (number of episodes of hypotension, hypertension and bradycardia) 2. Total dose and number of boluses of either drug required to maintain systolic blood pressure 3. Incidence of maternal nausea and vomiting 4. Neonatal outcome Apgar score Development of hypoxic ischaemic encephalopathy (HIE) Timepoint: 2 min and 5 min till the end of surgery

Countries

India

Contacts

Public ContactSurbhi Saini

Lady Hardinge Medical College

ranjusingh1503@yahoo.com9811151285

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026