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A study to determine the relation between tooth decay and composition of saliva

Correlation of Carbonic Anhydrase VI enzyme, Total proteins, Antioxidant levels of saliva and Dental caries in caries free and caries active children - a Case Control Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/01/017135
Enrollment
60
Registered
2019-01-17
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

Anjana Vasudevan
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children having enamel caries with DMFT/dmft greater than 5 and caries free children with DMFT/dmft equal to 0. Healthy children with a good record of general health and those who are not taking any medications are selected for the study after obtaining informed consent.

Exclusion criteria

Exclusion criteria: Children having deep dentinal caries and pulpally involved teeth, children having an abscess due to dental caries, children with salivary gland disorders, those with special health care needs, recent exposures to antibiotics (last 3 months), poor oral hygiene, presence of periodontal disease are excluded from participating in the study

Design outcomes

Primary

MeasureTime frame
Comparative estimation of levels of Carbonic anhydrase VI enzyme, Total proteins, antioxidant parameters in saliva of caries free and caries active children among age group 6-12 years.Timepoint: 3 months—

Secondary

MeasureTime frame
Comparative estimation of levels of Carbonic anhydrase VI enzyme, Total proteins, antioxidant parameters in saliva of caries free and caries active children among age group 6-12 years.Timepoint: 3 months—

Countries

India

Contacts

Public ContactDr Sridhar Nekanti

Manipal College of Dental Sciences,Manipal

sridhar.pedo@manipal.edu9886932642

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026