A study of the effectiveness and safety of Clonidine, added to local anaesthetic, in Stellate Ganglion block used for treatment of pain in Complex Regional Pain Syndrome.

Analgesic efficacy and safety of Clonidine as an additive to 0.25% Ropivacaine in Stellate Ganglion Block for the treatment of Complex Regional Pain Syndrome. A prospective randomised single blind study.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/01/017080

Enrollment

Registered

2019-01-15

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G905- Complex regional pain syndrome I (CRPS I)

Interventions

Intervention1: Ultrasound guided Stellate Ganglion Block: Before starting the intervention, all measures for resuscitation will be kept ready, including (1.) equipments for Intermittent Positive Press

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists grade 1, 2 and 3

Exclusion criteria

Exclusion criteria: 1.)Patients suffering from coagulation disorders 2.)Those who have any local infection at the puncture site 3.)Drug or alcohol abuse 4.)Patients taking beta blockers or alpha blockers for any reason 5.)Patients with baseline Heart Rate less than or equal to 60/min 6.)Presence of diabetic neuropathy 7.)Patient refusal to participate

Design outcomes

Primary

Measure	Time frame
To compare the Visual Analogue Scale (VAS) scores, Range of Motion and Edema scores between two groups of patients, one receiving 40 mg of Methylprednisolone and the other receiving 15 mcg of Clonidine, with 0.25% Ropivacaine for Stellate Ganglion BlockTimepoint: From the time of first visit to pain clinic to 2. 5 months after that.	—

Secondary

Measure	Time frame
1.)To study the adverse effects of Clonidine as an additive to 0.25% Ropivacaine for Stellate Ganglion Block 2.)To study the haemodynamic variations in the two groups during and for half an hour after the procedure 3.)To compare the improvement in quality of life between the two groups 4.)To compare the patient satisfaction score between the two groupsTimepoint: From the time of first visit to pain clinic to 2. 5 months after that.	—

Measure

Time frame

1.)To study the adverse effects of Clonidine as an additive to 0.25% Ropivacaine for Stellate Ganglion Block 2.)To study the haemodynamic variations in the two groups during and for half an hour after the procedure 3.)To compare the improvement in quality of life between the two groups 4.)To compare the patient satisfaction score between the two groupsTimepoint: From the time of first visit to pain clinic to 2. 5 months after that.

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Countries

India

Contacts

Public ContactDr Sreyashi Naskar

All India Institute of Medical Sciences, New Delhi

mayadehran@yahoo.com9873767991

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026