Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Dexmedetomidine nebulization: 1 microgram/kg dexmedetomidine in 3-4 ml normal saline will be administered as nebulization to patients 30 minutes before induction of anaesthesia
Control
Sponsors
Dr Satyajeet Misra
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients posted for elective surgery will be recruited into the trial after obtaining their written informed consent. The dexmedetomidine group will receive nebulization with 1 microgram/kg dexmedetomidine diluted in 3-4 ml normal saline 30 minutes before induction of anaesthesia. Heart rate and blood pressure responses to laryngoscopy and intubation will be recorded for 10 minutes after laryngoscopy. The normal saline group (control) will receive nebulization with normal saline (3-4 ml) 30 minutes before induction of anaesthesia and heart rate and blood pressure responses to laryngoscopy and intubation will be recorded for 10 minutes after laryngoscopy.
Exclusion criteria
Exclusion criteria: Patients who undergo emergency surgeries, have known or unanticipated difficult airway and those who are on anti-hypertensive medications will be excluded from the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in heart rate and blood pressure between the two groupsTimepoint: Upto 10 minutes following laryngoscopy | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative nausea and vomiting and sore throatTimepoint: First 2 hours following surgery | — |
Countries
India
Contacts
Public ContactDR SATYAJEET MISRA
AIIMS Bhubaneswar
Outcome results
None listed