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Effect Of Mangosteen Fruit Gel As Gum Medicine Along With Cleaning Of Teeth And Gums On Total Intoxicant Capacity Levels Of Gums Fluid In Pyorrhea Patients

Effect Of Mangosteen Pericarp Gel As Local Drug Delivery In Adjunct To Non-Surgical Periodontal Therapy On GCF Total Antioxidant Capacity Levels And Clinical Parameters In Chronic Periodontitis Patients- A Placebo Controlled, Split Mouth Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/01/017052
Enrollment
25
Registered
2019-01-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Intracrevicular administration of 4% mangostana gel:: For standardization, 0.1 ml of prepared MGA gel (4 mg/0.1 ml) will be loading into the hypodermic syringe with 24 gauge angulated b

Sponsors

Vinayaka A M
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient with the age range of 35 -60 years of either sexes. 2. Patients with Chronic periodontitis having probing depth (PD) >= 6mm and clinical attachment loss (CAL) >= 4mm around two or more teeth, in two or more sextants. 3. Patients with minimum of 20 teeth.

Exclusion criteria

Exclusion criteria: 1. Patients with aggressive periodontitis. 2. Patients who received any surgical/non â?? surgical periodontal therapy in the preceding 3 months. 3. Patient who have used antibiotics, anti-inflammatory agents ,mouth rinses and topical gels in last 3 months. 4. Patient with habits like of Smoking or Tobacco chewing or Alcohol consumption. 5. Patients with an uncontrolled Diabetes, Hypertension and Immunocompromised patients. 6. Pregnant or lactating mothers. 7. Patients on anticoagulant therapy. 8. Patients who were non-compliant.

Design outcomes

Primary

MeasureTime frame
1. To compare the average probing depth between experimental and control groups at the end of 3 months.Timepoint: baseline to three months

Secondary

MeasureTime frame
2. To compare the average clinical attachment level between experimental and control groups at the end of 3 months.Timepoint: baseline to three months;3. To compare the average total antioxidant capacity levels in the GCF between experimental and control groups at the end of 3 months.Timepoint: baseline to three months

Countries

India

Contacts

Public Contactvinayaka a m

bapuji dental college and hospital

somugayathri1968@gmail.com9886593224

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026