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Comparison of clonidine and magnesium sulphate in patients of ear nose and throatsurgeries.

Comparison of intravenous magnesium sulphate and clonidine in attenuating the hemodynamic response, anesthetic consumption and postoperative recovery in patients undergoing elective ENT surgeries.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/01/017048
Enrollment
76
Registered
2019-01-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H679- Otitis media in diseases classified elsewhere, unspecified ear

Interventions

Intervention1: Group M: Group M (Magnesium Sulphate): inj. MgSO4 20mg/kg intravenously over a period of 15 minutes before induction and 5mg/kg/hour by continuous infusion intraoperatively & will be s

Sponsors

MDM hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)ASA group 1&2. 2)patients posted for eiective ENT surgeries who require GA and airway maintenance with ET intubation. 3)prior informed and written consent given by the patients. 4)age group between 18 to 60 years of either sex

Exclusion criteria

Exclusion criteria: 1)patients not willing to be part of this study. 2)patients who are having known allergy to the study drugs. 3)SBP 4)pt. with history of mysthenia gravis, muscular dystrophy or any other neuromuscular disease. 5)pts. with history of epilepsy/seizure disorder. 6)pts. who are taking antihypertensive medications. 7)pregnant patients.

Design outcomes

Primary

MeasureTime frame
to study and compare the effect of intravenous magnesium sulphate 20 mg per kg bolus followed by 10mg/kg/hr infusion and intravenous clonidine 2 microgram /kg bolus folloed by 0.5 microgram /kg/hrinfusion in attenuating the hemodynamic respnse to -1 laryngoscopy and endotracheal intubation ,extubation and recovery Timepoint: till recovery of patients

Secondary

MeasureTime frame
anaesthetic consumption during surgeryTimepoint: till recovery of patients

Countries

India

Contacts

Public ContactDr Shobha Ujwal

DR S.N. MEDICAL COLLEGE,JODHPUR

dr.amanchoudhary@gmail.com9413904622

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026