Study to find out if dexamethasone is used to fill cuff of tube placed in windpipe during operation will reduce sore throat, cough and hoarseness of voice after surgery.

Effect of intracuff dexamethasone on post operative sore throat, hoarseness of voice and cough: A comparison with normal saline

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/01/016992

Enrollment

Registered

2019-01-08

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N979- Female infertility, unspecified

Interventions

Intervention1: Dexamethasone 0.1mg/kg body weight: Dexamethasone 0.1mg/kg body weight in saline will be used to fill cuffs of endotacheal tubes Control Intervention1: Normal saline: 0.9% normal saline

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists (ASA)Physical status 1,2 patients who will be undergoing short laparoscopic surgery lasting less than 2 hours like diagnostic pelvic laparoscopy, and laparoscopic sterilization

Exclusion criteria

Exclusion criteria: those who will require three or more attempts at laryngoscopy,nasogastric tube insertion and/or who will require a bougie for intubation

Design outcomes

Primary

Measure	Time frame
To compare the effect of intracuff dexamethasoneon incidence and severity of post operative sore throat (POST)Timepoint: 24 hours postoperatively	—

Secondary

Measure	Time frame
comparison of the effect on post operative hoarseness of voice(POHV) and cough (POC).Timepoint: 2, 6, 12 and 24 hours postoperative	—

Countries

India

Contacts

Public ContactDr Naina Narayani

Amrita Institute of medical Sciences

sunilrajan@aims.amrita.edu9446500223

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026