A clinical trial to assess difference between use of site specific irrigation and lasers along with deep cleaning for management of patients with chronic periodontitis

Comparative evaluation of non-surgical periodontal therapy combined with a topical desiccant agent or diode lasers for the management of chronic periodontitis- a prospective randomized placebo controlled clinical study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/01/016964

Enrollment

Registered

2019-01-08

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z006- Encounter for examination for normal comparison and control in clinical research program

Interventions

Intervention1: HybneX gel: Topical desiccant agent Control Intervention1: Diode laser: Soft tissue laser

Eligibility

Inclusion criteria

Inclusion criteria: Patients willing to voluntarily participate with minimum of 20 functional natural teeth and patients with moderate to severe form of periodontitis with at least two teeth with periodontal pocket depth more than or equal to 6mm and clinical attachment level more than or equal to 3mm

Exclusion criteria

Exclusion criteria: 1. Subjects allergic to sulfonated compounds. 2. Subjects with any systemic disorders 3. Subjects who have used antibiotics or anti-inflammatory drugs for last 3months. 4. Pregnant and lactating women

Design outcomes

Primary

Measure	Time frame
The primary outcome in the present study will be the reduction in pocket probing depth and gain in clinical attachment levels in test groupsTimepoint: 15 days and 3rd month	—

Secondary

Measure	Time frame
The secondary outcome will be the reduction in inflammatory mediators (Interleukin 1Î² and TNF- Î±) in test groupsTimepoint: 15 days and 3rd month	—

Countries

India

Contacts

Public ContactAnjale Rajagopal

Manipal College of Dental Sciences

jothi.v@manipal.edu9845208532

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026