Health Condition 1: K053- Chronic periodontitis
Conditions
Interventions
Intervention1: 1% curcumin chip in biodegradable hydroxy propyl methyl cellulose vehicle: Following routine full mouth scaling and root planing within 48 hours, a single 4x5x0.5mm chip of 1% curcumin
Sponsors
Dr Riya Achamma Daniel
Eligibility
Inclusion criteria
Inclusion criteria: 1 Systemically healthy individuals 2 Presence of a minimum of 20 teeth in the oral cavity 3 Localised periodontal pockets with probing depths greater than 4mm i.e., Periodontitis in its stages 2 and 3, as described by the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions, and published by the American Academy of Periodontology (AAP)
Exclusion criteria
Exclusion criteria: 1 Known allergy to curcumin and/ or hydroxyl propyl methyl cellulose 2 Systemic diseases and/or Inflammatory conditions, Obesity 3 Former or current tobacco users 4 Chronic consumption of alcohol 5 Use of anti-inflammatory drugs and antibiotics over the past 3 months 6 Periodontal therapy in any form, surgical or non surgical in the past 6 months 7 Pregnant and lactating mothers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Levels of interleukin 1 beta in the gingival crevicular fluid quantified by ELISA in picogram per milliliterTimepoint: 1 month from baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| Probing pocket depth Clinical attachment level Gingival index by Loe and Silness in 1963 Plaque index by Silness and Loe in 1964 Timepoint: 1 month and 3 months from baseline | — |
Countries
India
Contacts
Public ContactDr Riya Achamma Daniel
KLE Societys Institute of Dental Sciences
Outcome results
None listed