A study to evaluate the rate of occurrence, causes, treatment and outcome of sepsis in Asian Intensive care units.

Conditions

Health Condition 1: A419- Sepsis, unspecified organism

Do SN, Dao CX, Nguyen TA, Nguyen MH, Pham DT, Nguyen NT, Huynh DQ, Hoang QTA, Bui CV, Vu TD, Bui HN, Nguyen HT, Hoang HB, Le TTP, Nguyen LTB, Duong PT, Nguyen TD, Le VH, Pham GTT, Bui GTH, Bui TV, Pham TTN, Nguyen CV, Nguyen AD, Phua J, Li A, Luong CQ.

2023-03-1429 citations

10.1136/bmjopen-2022-064870

Predictive validity of the quick Sequential Organ Failure Assessment (qSOFA) score for the mortality in patients with sepsis in Vietnamese intensive care units

Do Ngoc Son, Chinh Quoc Luong, My Ha Nguyen, Dung Thi Pham, Natalie Nguyễn et al. (25 authors)

PLoS ONE2022-10-1414 citations

10.1371/journal.pone.0275739

Epidemiology, Management, and Outcomes of Sepsis in ICUs among Countries of Differing National Wealth across Asia

Andrew Li, Lowell Ling, Hanyu Qin, Yaseen M. Arabi, Sheila Nainan Myatra et al. (29 authors)

American Journal of Respiratory and Critical Care Medicine2022-06-2887 citations

10.1164/rccm.202112-2743oc

Interventions

Intervention1: NIL: NIL Control Intervention1: Nil: Nil

Eligibility

Inclusion criteria

Inclusion criteria: 1.All adult patients who are admitted to the participating ICUs from 0000Hr (midnight) to 2359Hr (midnight) of the day of data collection for sepsis.They can be patients admitted from the emergency departments, or transferred from anywhere in the same hospital or other hospitals or elsewhere. 2.All adult patients who were admitted for sepsis to the participating ICUs prior to the day of data collection and who are still in the participating ICUs on the day of data collection.

Exclusion criteria

Exclusion criteria: 1.Patients younger than 18 years old. 2.Neurosurgical patients, defined as patients who are admitted to the ICU after or pending neurosurgical interventions. 3.Cardiac patients, defined as patients who are admitted to the ICU after cardiac surgery, for acute myocardial infarction without shock or respiratory failure, and for arrhythmias.

Design outcomes

Primary

Measure	Time frame
1. Prevalence, cause and outcome of sepsis in Asian Intensive Care Units 2.All-cause in-hospital mortality 3.All-cause ICU mortality. 4.Length of ICU stay. 5.Length of total hospital stay.Timepoint: We will follow all patients till hospital discharge, death in the ICU/hospital, and up to 90 days post-enrolment, whichever was earliest	—

Secondary

Measure	Time frame
1.time to management of sepsis with a focus on recommendations by the Surviving Sepsis Campaign guidelinesTimepoint: for total 4 days 0000Hr (midnight) to 2359Hr (midnight) of the day of data collection for sepsis for study duration of 1 year;2.To compare the prevalence, causes, outcomes, and management of sepsis in Asian ICUs in high, middle, and low-income countries and regions, defined according to the World Bank classification.Timepoint: for total 4 days 0000Hr (midnight) to 2359Hr (midnight) of the day of data collection for sepsis for study duration of 1 year;3.To specifically study the prevalence and outcomes of sepsis as a result of malaria, dengue, tuberculosis, cholera, and Salmonella infections, as well as culture-negative sepsis.Timepoint: for total 4 days 0000Hr (midnight) to 2359Hr (midnight) of the day of data collection for sepsis for study duration of 1 year	—

Measure

Time frame

1.time to management of sepsis with a focus on recommendations by the Surviving Sepsis Campaign guidelinesTimepoint: for total 4 days 0000Hr (midnight) to 2359Hr (midnight) of the day of data collection for sepsis for study duration of 1 year;2.To compare the prevalence, causes, outcomes, and management of sepsis in Asian ICUs in high, middle, and low-income countries and regions, defined according to the World Bank classification.Timepoint: for total 4 days 0000Hr (midnight) to 2359Hr (midnight) of the day of data collection for sepsis for study duration of 1 year;3.To specifically study the prevalence and outcomes of sepsis as a result of malaria, dengue, tuberculosis, cholera, and Salmonella infections, as well as culture-negative sepsis.Timepoint: for total 4 days 0000Hr (midnight) to 2359Hr (midnight) of the day of data collection for sepsis for study duration of 1 year

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Countries

Bangladesh, China, Hong Kong, India, Indonesia, Iran (Islamic Republic of), Japan, Malaysia, Pakistan, Philippines, Republic of Korea, Saudi Arabia, Singapore, Taiwan, Thailand, Viet Nam

Contacts

Public ContactDr Sheila Nainan Myatra

Tata Memorial Center

sheila150@hotmail.com09820156070

Outcome results

None listed