Comparison of toothpaste containing mango twig and market available toothpaste on oral bacteria and debris among 12-15 years old children in Davangere city.

Comparison of efficacy of dentifrices containing mangifera indica extract and fluoride on salivary streptococcus mutans count and plaque accumulation among 12 â?? 15 years school children in Davangere city â?? A randomized controlled trial

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/01/016897

Enrollment

Registered

2019-01-04

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B999- Unspecified infectious disease

Interventions

Intervention1: TEST DENTIFRICE- Mangifera indica extract: Composition include all the basic ingredients of toothpaste and therapeutic agent as Mangifera indica extract at a concentration of 0.2%w/w T

Eligibility

Inclusion criteria

Inclusion criteria: 1.Subjects whose parents will give consent for their children to participate in study. 2. Subjects having at least one cavitated active carious lesion A cavitated active lesion â?? is a well-defined cavity with exposed dentin, yellowish or light brown in colour, which feels soft on gentle probing. 3. Having a streptococcus mutans count of equal to or more than 105 CFU per ml of saliva (microbiological selection criteria) 4. Subjects with a baseline mean plaque index score of at least 1.5 as determined by the use of the Turesky modification of the Quigley-Hein Plaque Index. 5. Subjects with presence of more than 20 scoreable teeth in the oral cavity

Exclusion criteria

Exclusion criteria: 1. Subjects on medications and subjects with systemic diseases that affect their salivary flow rate. 2. History of hypersensitivity to any product used in the study 3. History of antibiotic therapy in the previous one month till the start of the study. 4. Subjects who will be unable to comply with the study appointment Schedules 5. Subjects using orthodontic appliances 6. Subjects using adjunctive oral hygiene aid like mouthwash

Design outcomes

Primary

Measure	Time frame
1. To assess and compare the antiplaque and antibacterial efficacy of Mangifera indica extract dentifrice, commercially available Fluoridated dentifrice (Colgate total care) and a Placebo dentifrice on salivary Streptococcus mutans levels and plaque levels among 12 â?? 15 years old school children in Davanagere cityTimepoint: 1. 21 days after intervention	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Sapna B

Bapuji Dental College and Hospital

sapnaprasanna@gmail.com9448038191

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026