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Comparison of serum and placental levels of an enzyme (angiotensin-converting enzyme)and a vasodilator (nitric oxide) in preeclampsia patients

Comparison and correlation of serum and placental levels of angiotensin-converting enzyme (ACE) and nitric oxide (NO) in preeclampsia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/01/016890
Enrollment
124
Registered
2019-01-03
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O149- Unspecified pre-eclampsia

Interventions

None listed

Sponsors

Kasturba Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Cases: Patients diagnosed with preeclampsia who are in their 3rd trimester of pregnancy Controls: Healthy subjects in the 3rd trimester of pregnancy who do not exhibit symptoms of preeclampsia and gestational diabetes.

Exclusion criteria

Exclusion criteria: Pregnant subjects showing complications such as gestational diabetes, hypertension, etc are excluded.

Design outcomes

Primary

MeasureTime frame
Difference in levels of serum and placental angiotensin-converting enzyme (ACE) and nitric oxide (NO) between case and control groupsTimepoint: Samples are collected in 3rd trimester of pregnancy—

Secondary

MeasureTime frame
Correlation between serum ACE and NO Correlation between placental ACE and NOTimepoint: Samples are collected in 3rd trimester of pregnancy—

Countries

India

Contacts

Public ContactDr Revathi P Shenoy

Kasturba Medical College, MAHE, Manipal

revathi.shenoy@manipal.edu9449367734

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026