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To study the effect of platelet rich plasma prepared from patients own blood( blood product)on growth of uterine lining and reproductive outcome in women with persistent thin endometrial lining during IVF

To evaluate the role of autologous platelet rich plasma in women with refractory thin endometrium and subsequent reproductive outcome during IVF

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/12/016799
Enrollment
50
Registered
2018-12-31
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O00-O08- Pregnancy with abortive outcome

Interventions

Intervention1: Autologous platelet rich plasma (PRP): HRT will be given to all the participants for endometrial preparation. PRP will be prepared from autologous blood using two step centrifuge proces

Sponsors

AIIMS Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Infertile women registered in IVF clinic 1. Thin endometrium ( 2. Previous history of cycle cancellation in FET cycles due to persistent thin endometrium 3. Hysteroscopically normal endometrial cavity

Exclusion criteria

Exclusion criteria: 1. Distorted endometrial cavity because of recurrent adhesions 2. Patients not willing to participate in study

Design outcomes

Primary

MeasureTime frame
Increased endometrial thickness (more than 7mm)Timepoint: 48 hours after intrauterine infusion of PRP—

Secondary

MeasureTime frame
Biochemical Pregnancy rateTimepoint: beta - hCG value of more than 100IU detected 16 days after embryo transfer;Clinical pregnancy rateTimepoint: presence of intrauterine gestational sac with cardiac activity at 6 weeks;Implantation rateTimepoint: number of gestational sacs divided by number of embryos transferred multiplied by 100 at 6 weeks of pregnancy—

Countries

India

Contacts

Public ContactDr Yogita Dogra

AIIMS

drneetasingh@yahoo.com9818506855

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026