Health Condition 1: R508- Other specified fever
Conditions
Interventions
Intervention1: paracetamol: to assess time taken to decrease single episode of fever spike to normal range
Intervention2: mefenamic acid and paracetamol: First group will receive paracetamol 15mg/kg/d
Sponsors
Dr Amruta Loya
Dr Mohd Saeed Siddiqui
Eligibility
Inclusion criteria
Inclusion criteria: Children between 6 months and 5years of age, of either sex and with a Axillary temperature of 38°C/100.4 F or above included in the study
Exclusion criteria
Exclusion criteria: If patient received any antipyretic drug in previous 6 hrs History of hypersensitivity to study medication patients receiving antibiotics Patients admitted in ICU Patients with active gastrointestinal bleeding Known coagulopathy Chronic renal, liver and cardiac failure Pt medicated with warfarin, heparin or any other anti hypertensives Any medication that could interfere with the study was not permitted during the study. Any clinical adverse event, serious illness or other medical condition in view of investigator/treating doctor, in which continued participation was not in the best interest of the subject Voluntary decision of legal guardian/patient to withdraw from the study Any patient who required the use of an unacceptable concomitant medication or intervention that interfered with the study If febrile seizure/convulsions occurred to the child during the study. If the patients temp does not drop to normal range , then patient will be excluded from the study If body temp increases above 104 degree farenheit or decreases below 96.5 degree farenheit.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study the Antipyretic effect of Paracetamol and Mefenamic acid in treatment of febrile childrenTimepoint: 15mins | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the time taken to decrease the single episode of fever to normal range by Paracetamol[20mg/kg/dose] and Mefenamic acid.[6mg/kg/dose] To compare tolerability of Paracetamol and Mefenamic acid in children. To compare the effect of Paracetamol and Mefenamic acid in different intensities of fever. To know the duration of antipyretic effect of Paracetamol and Mefenamic acid. Timepoint: 15 mins | — |
Countries
India
Contacts
Public ContactDr Amruta Loya
MGM Medical College and Hospital
Outcome results
None listed