Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Identifying the ideal mixing ratio of ketamine and propofol for haemodynamic stability on induction: four groups with diffent doses of ketamine and propofol are used to find the ideal d
Sponsors
Department of Anesthesiology and Critical Care BATRA HOSPITAL MEDICAL RESEARCH CENTRE NEW DELHI
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age group 18-65 years. 2. Either sex 3. ASA status I&II 4. BMI of 18.5-30. 5. Patients posted for elective surgeries under general anaesthesia
Exclusion criteria
Exclusion criteria: 1. Hypertension and IHD 2. Morbid obesity 3. H/O chronic pain. 4. Patients on drugs like β blockers or calcium channel blockers. 5. Pregnant or lactating women 6. H/O Substance abuse 7. Patients with psychological disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Combining propofol and ketamine results in the hypotension and bradycardia caused by propofol getting counteracted by hypertension and tachycardia caused by Ketamine, thereby resulting in better hemodynamic stability on induction[9]. Ketamine reduces the pain on injection of propofol which in turn attenuates the emetic effect and emergence reaction caused by ketamine. Timepoint: before induction at 1 minute 2 minutes and 3 minutes After intubation at 2 minutes 5 minutes and 10 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| post op emergence, nausea and vomitingTimepoint: immediate post op and 1st and 2nd hour post operation | — |
Countries
India
Contacts
Public ContactDr Pavan Gurha
Batra Hospital & Medical Research Center
Outcome results
None listed