Health Condition 1: N20- Calculus of kidney and ureter
Conditions
Interventions
Intervention1: group S: Stroke volume variation directed intaoperative fluid therapy
Control Intervention1: group C: conventional fluid therapy
Sponsors
University College of Medical Sciences and GTB Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Those patients who are scheduled for pcnl (percutaneous nephrolithotomy) surgery under general anaesthesia
Exclusion criteria
Exclusion criteria: patients 65 years Those receiving renal replacement therapy or with transplanted kidney or clinical evidence of significant dysrhythmia, cardiac failure,stroke, coronary heart disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of early postoperative AKI as defined by the KDIGO criteria (i.e., serum creatinine with/without urine output)Timepoint: Preoperative, 24 hours and 48 hours postoperatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| change in estimated GFR which will be calculated using MDRD equation.Timepoint: difference between serum creatinine values preoperatively as well as 24 hours and 48 hours postoperatively.;change in serum creatinine valuesTimepoint: difference between serum creatinine values preoperatively and postoperatively at 24 hours and 48 hours;severity of AKI as defined by KDIGO criteriaTimepoint: estimation of serum creatinine values preoperatively as well as 24 hours and 48 hours postoperatively urine output will be considered if estimates of hourly collection are available | — |
Countries
India
Contacts
Public ContactAparna Mohan
University College of Medical Sciences and GTB Hospital
Outcome results
None listed