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comparision between the effects of plain chloroprocaine and chloroprocaine with fentanyl in spinal anaesthesia

A prospective randomised double blinded study to assess the efficacy of subarachnoid blockade with or without addition of fentanyl 25mcgs to 1%-chloroprocaine in endoscopic urologic surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/12/016687
Enrollment
106
Registered
2018-12-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N398- Other specified disorders of urinary system

Interventions

Intervention1: Chloroprocaine , Fentanyl: chloroprocaine is a Ester local anaesthetic drug. Dose:30mg or 35mg depending on the group Route:spinal Frequency:single dose. Fentanyl is an opioid. Dose:25m

Sponsors

Sri Ramachandra Institute of Higher Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing endoscopic urologic surgeries ASA-I,II

Exclusion criteria

Exclusion criteria: Patient refusal Allergy to local anaesthetics Patient on anticoagulants or bleeding disorders Infection at site of injection

Design outcomes

Primary

MeasureTime frame
Onset of sensory blockade Maximum height of block achieved Onset time for complete motor blockade Regresssion time to L1 and return of bromage score to 0 Timepoint: sensory level will be assessed after three minutes of drug injection. Thereafter, sensory level is checked for every , 3min until 15min, every 5min until the end of surgery and then for every 10min for 60min and every 15min until block regresses to L1. Using Bromage scale Motor block is assessed For every 3min for 15min At the beginning and at the end of the surgery After the surgery for every 10min for 60min, then every 15minutes until the block regress to S2.

Secondary

MeasureTime frame
Any head tilt Time to first postoperative analgesia Any adverse eventsTimepoint: Vitals(BP,HR,RR,SPO2)noted for every 5min interval from the starting of surgery to end of surgery and then every 15min until block regressess to L1.

Countries

India

Contacts

Public ContactJanga Siddhartha Reddy

Sri Ramachandra Institute of Higher Education and Research

makilandeswari@yahoo.com9840636238

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026