Health Condition 1: M959- Acquired deformity of musculoskeletal system, unspecified Health Condition 2: E119- Type 2 diabetes mellitus without complications
Conditions
Interventions
Intervention1: hydroxychloroquine based regimen: Combination of drugs containing Hydroxychloroquine
Tablet Hydroxychloroquine 200mg once daily
if needed escalated to 400mg once daily
Control Interven
Sponsors
Dr Asha B
Sri Devaraj Urs Academy of Higher Education and Research
Eligibility
Inclusion criteria
Inclusion criteria: 2) Rheumatoid arthritis diagnosed based on American College of Rheumatology criteria (both seropositive and seronegative are included) 3) Type II diabetes with any one of the oral drug for diabetes 4) Fasting blood sugar 126-250 mg/dl and Post prandial blood sugar 200- 350mg/dl 5) HbA1c levels in the range of 6.6- 12%
Exclusion criteria
Exclusion criteria: 1) History of taking chloroquine and its derivatives, insulin preparations and corticosteroids or other hormone derivatives in the past 3 months 2) History of allergy to hydroxychloroquine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) To determine the effect of hydroxychloroquine on Fasting Blood Sugar (FBS), Post Prandial Blood Sugar (PPBS) and Glycated Hemoglobin (HbA1C) in patients with rheumatoid arthritis and type II diabetes mellitusTimepoint: 3 and 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 2) To assess the adverse effects in hydroxychloroquine based and non hydroxychloroquine based regimen in the above mentioned patients.Timepoint: 3 and 6 months | — |
Countries
India
Contacts
Public ContactDr Asha B
Sri Devaraj Urs Medical College
Outcome results
None listed