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Ultrasound-guided Quadratus Lumborum block for postoperative pain after laparoscopic nephrectomy

Ultrasound-guided Quadratus Lumborum block versus conventional intravenous opioid analgesia for postoperative pain after laparoscopic nephrectomy: A randomized controlled study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/12/016677
Enrollment
60
Registered
2018-12-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: N29- Other disorders of kidney and ureter in diseases classified elsewhere

Interventions

Intervention1: group QLB: To be given quadratus lumborum block with 0.4ml/kg ml of 0.25% Inj. Bupivacaine + 0.5 mcg/kg of dexmedetomidine. Control Intervention1: Group CON: Conventional systemic anal

Sponsors

Seth GS medical college and KEM hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adult patients (18 -65yrs) 2. ASA 1 and ASA 2. 3. Patients undergoing elective laparoscopic nephrectomy under general anaesthesia. 4. Patients able to give informed consent

Exclusion criteria

Exclusion criteria: 1. Hypersensitivity to local anaesthetic drug. 2. Bleeding disorders / patients on anticoagulant drugs. 3. Patients with compromised renal and liver function, uncontrolled diabetes, severe cardiovascular and respiratory disease. 4. Infection, trauma, scar or sinuses at the site of block. 5. Patients unable to speak or understand the verbal command. 6. Morbidly obese patient (BMI >40kg/m2) 7. Anticipated difficult airway

Design outcomes

Primary

MeasureTime frame
To assess the analgesic efficacy of a single injection quadratus lumborum block versus opioid analgesia using VAS pain scores during the first 48 postoperative hours and, ( outcome measure), Total amount of analgesic consumed over the first 48 hours postoperatively. (outcome measure) Timepoint: postoperatively at 1, 2 , 4, 6, 8, 12, 24, 48 hours—

Secondary

MeasureTime frame
1. To assess safety of the block- assessing complications like local anaesthetic toxicity, sedation, motor blockade. Complications related to intravenous analgesics like nausea, vomiting ,sedation , delayed recovery, respiratory depression. 2. Ease of performance of block in terms of time taken and number of attempts. 3. To assess the level of patient satisfaction with respect to postoperative pain control-with likert 4 point scale(outcome measure) Timepoint: postoperatively at 1, 2 , 4, 6, 8, 12, 24, 48 hours—

Countries

India

Contacts

Public ContactDr Isha Singhal

Seth GSMC and KEM hospital

ishasinghal07@gmail.com9825639938

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026