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Antibiotics prophylaxis in Live Liver Donors

Comparison of 9 doses vs 3 doses of Post Operative antibiotics in Live Liver Donors: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/12/016664
Enrollment
108
Registered
2018-12-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Dose: 4.5 g/ each dose Route: intra venous Total doses: 9 doses: one pre operative, one intra operative and seven post operative Interval between 2 doses : 8 hours: Piperacillin + Tazob

Sponsors

Institute of liver and biliary sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patient undergoing donor hepatectomy consent for the study

Exclusion criteria

Exclusion criteria: Patients refusing consent for inclusion in the study

Design outcomes

Primary

MeasureTime frame
The number of infective complications (CDC guidelines) in post operative period will be compared among patients receiving 3 doses vs patients receiving 9 doses of antibiotics.Timepoint: Post op day 7 and 15 (Study duration 1 year)

Secondary

MeasureTime frame
Risk factors associated with infective complications will be evaluated in patients undergoing donor hepatectomy. Risk factors will be evaluated as per risk factor assessment proforma. Risk factors to be evaluated are: Pre- Operative Age Gender Liver attenuation index Intra- Operative factors: Duration of surgery Type of graft Volume of graft Volume of remnant liver Blood Loss Blood Transfusion Post - operative factors: Days of hospital stay Timepoint: Post op day 7 and 15 (Study duration 1 year)

Countries

India

Contacts

Public ContactSahil Gupta

Institute of liver and biliary sciences

viniyendra@yahoo.co.uk

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026