FindTrial
Sign In

Patients presenting to our outpatient department of dentistry requiring removal of their lower third molar tooth will be given orally Dexamethasone therapy either before or after the tooth removal to compare its effectiveness.

A Comparative study of efficacy of preoperative versus postoperative oral Dexamethasone therapy for impacted lower third molar surgical extraction.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/12/016663
Enrollment
126
Registered
2018-12-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Oral administration of 8 mg Dexamethasone.: Dexamethasone 8mg will be administered through oral route.In Group 1 it will be given one hour before the extraction of lower third molar and

Sponsors

Nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients of either sex and age groups from 18-45 years. 2.Patients who are healthy, non smoking, with no or minimal alcohol use--ASA I; Or patients with well controlled mild to moderate systemic disease or are healthy ASA I patients who demonstrate a more extreme anxiety and fear toward dentistry--ASA II. 3.All types of only fully impacted lower third molars are considered. 4.Patients should be having good oral hygiene.

Exclusion criteria

Exclusion criteria: 1. Pregnant / lactating females. 2.Subjects who were on antibiotics and/or anti-inflammatory drugs steroids or any other medications within 24 hours of the study entry. 3 Subjects with any active medical illness or dental diseases that can affect the surgical procedure.

Design outcomes

Primary

MeasureTime frame
Better welfare of the patients by helping them to return to their normal activity following surgical procedure of impacted mandibular third molar.Timepoint: At 2nd,5th and 7th post operative days.—

Secondary

MeasureTime frame
1.Evaluating post surgical complications like pain, oedema and limited mouth opening (trismus). 2.Oral Health Related Quality of Life(OHRQol) in both the groups during the study period using Oral Health Impact Profile Questionnaire (OHIP-14) SCALE. 3.To observe and record the adverse drug reactions,if any, in both the groups during the study period. Timepoint: At 2nd,5th and 7th post operative days.—

Countries

India

Contacts

Public ContactDr Jaya Sharma

RUHS College of Medical Sciences,Jaipur,Rajasthan,India.

pharmacologyruhscms@gmail.com9530028204

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026