FindTrial
Sign In

A clinical trial to compare the postoperative pain relieving effect of intraoperative ketamine and fentanyl infusion in major abdominal surgeries

Comparison of low dose ketamine and low dose fentanyl on postoperative analgesia in adult patients undergoing laparoscopic abdominal surgery. A randomized double blinded controlled trial - Not applicable

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/12/016649
Enrollment
231
Registered
2018-12-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Ketamine: Intraoperative infusion of ketamine at rate of 0.25 mg/kg/hr till surgical closure Control Intervention1: Fentanyl IV: Intraoperative Fentanyl infusion 0.5 mcg/kg/hr till surg

Sponsors

AIIMS Jodhpur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American society of Anesthesiologists physical status 1 and 2

Exclusion criteria

Exclusion criteria: Patients less than 18 yrs and more than 60 yrs Patient refusal to participate in the study Patient with Opioid abuse, long term analgesic use or alcohol consumption Patient with known allergy or contraindications to any of the drugs used. Patient converted to open cholecystectomy Body mass index (BMI) less than 18 kg/m2 greater than 35 kg/m2

Design outcomes

Primary

MeasureTime frame
Assessment of effect of intraoperative low dose ketamine and low dose fentanyl on postoperative opioid analgesic requirement in adults undergoing laparoscopic abdominal surgeryTimepoint: Opioid analgesic requirements for 24 hrs—

Secondary

MeasureTime frame
Assessment of effect of intraoperative low dose ketamine on postoperative VAS scores in adults undergoing laparoscopic abdominal surgeryTimepoint: Post operative VAS scores for 8 hrs;To assess the effect of intraoperative low dose ketamine infusion on time required for extubationTimepoint: From closure of inhalational anaesthetics to extubation time;To assess the presence of side effects of ketamine postoperatively with intraoperative low dose ketamine infusionTimepoint: Assessment for 8 hrs—

Countries

India

Contacts

Public ContactMussavvir Agha

AIIMS Jodhpur

docbpali@gmail.com09588089378

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026