To test the effectiveness of Vitamin C to decrease pneumonia in mechanically ventilated patients

A Randomized controlled trial to examine the usefulness of Vitamin C to reduce incidence of Ventilator associated pneumonia

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/12/016634

Enrollment

Registered

2018-12-12

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B95-B97- Bacterial and viral infectious agents Health Condition 2: B95-B97- Bacterial and viral infectious agents

Interventions

Intervention1: Vitamin C and placebo: Cases to be given Vitamin c and controls to be given placebo Control Intervention1: Vitamin C and placebo: Cases to be given Vitamin C and controls to be given pl

Eligibility

Inclusion criteria

Inclusion criteria: All patients ventilated on day 1 of hospitalisation

Exclusion criteria

Exclusion criteria: All patients ventilated in other hospital and then referred

Design outcomes

Primary

Measure	Time frame
To examine the usefulness of Vitamin C to reduce incidence of Ventilator associated pneumonia.Timepoint: The time to development of polymorphic cell reaction and time to development of CDC criteria for VAP will be examined in both case and control groups	—

Secondary

Measure	Time frame
Duration of ventilation and hospitalization will be recorded.Timepoint: Duration of ventilation and hospitalization	—

Countries

India

Contacts

Public ContactDr Jacob M Puliyel

St. Stephens Hospital

puliyel@gmail.com9868035091

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026