None listed
Conditions
Interventions
Intervention1: i-PRF for management of intrabony defects: i-PRF will be prepared following the protocol given by Mourao et al.2
To obtain thei-PRF,blood collection is performed using 10ml tubes witho
it is possible to observe an orange color area in the tube(i-PRF) and the remaining blood material below. The tubes are opened carefully,to avoid homogenization of the material. Then i-PRF is collecte
Sponsors
self funded
Eligibility
Inclusion criteria
Inclusion criteria: )Periodontitis patient in the age group of 19-65yrs of both the gender,diagnosed based on A new classification scheme for periodontal and periâ??implant diseases and conditions â?? Introduction and key changes from the 1999 classification.6 2) Full mouth plaque scores(PI 3) Etiological periodontal therapy completedat least 3 months prior to the screening. 4) Presence of one natural tooth having avertical defect with residual probingDepth(PD) > 6 mm and radiographicintrabony component > 3mm and radiographic angle of defect >37 degree.
Exclusion criteria
Exclusion criteria: Smoking habits 2) Contraindications for periodontal therapy 3) Systemic diseases affecting periodontal healing. 4) Pregnancy and lactation. 5) History of periodontal surgery or prosthetic restorations at the experimental teeth. 6) Clinical evidenceof furcation defects at the surgical site. 7) Teethwhich are pathologicallymobile. 8)Non vital teeth or trauma from occlusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measurement is the radiographic bone fill.Timepoint: 3 months,6 months,9 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Pocket probing depth; 2) Gingival marginal level (GML)and Clinical attachment level (CAL) measured from customized acrylic stents with grooves to ensure reproducibility using the probe. 3) Full mouth plaque scores(FMPS) andFull mouth bleeding scores(FMBS) are also calculated as the percentage of gingival units (6 sites per tooth) around all teeth that revealed PI or BoP. levels of PDGF-BB in wound fluidTimepoint: 0 months,3 months,6 months and 9 months after the treatment for clinical parameters.ofPDGF-BB in the wound fluid collected from the surgical sites at 1stday,7th day, 14thday,21stday and at 30th day following surgical treatment. | — |
Countries
India
Contacts
Public ContactDrSmithaK
Government Dental college and Research institute
Outcome results
None listed