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Randomised, triple arm, comparative study of duration of pain free period between two routes of administration of a drug when given in addition to anaesthetic drug injected near nerve to block pain with the help of ultrasound machine.

Randomised, triple arm, comparative study of duration of analgesia between intravenous & perineural dexamethasone as adjuvant to local anaesthetic in ultrasound guided supraclavicular brachial plexus block.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/12/016524
Enrollment
105
Registered
2018-12-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexamethasone as adjuvant to local anaesthetic in supraclavicular brachial plexus block.: Dexamethasone as adjuvant to local anaesthetic is known to prolong the duration of sensory and

Sponsors

M S Ramaiah Medical College and Hospital
Lead Sponsor
Dr Ankhitha R S
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: ASA I , II , III Upper extremity surgery

Exclusion criteria

Exclusion criteria: Body Mass Index > 35 kg m-2 Surgery duration > 180 minutes Contraindications to peripheral nerve block - bleeding diathesis, local skin infection, coagulation abnormalities Pregnancy Severe cognitive/psychiatric history Neuropathy of any cause Clavicular fracture Severe respiratory disease Chest/shoulder deformities on operative side Allergy to Dexamethasone/local anaesthetic Pre-existing chronic pain requiring opioid medications

Design outcomes

Primary

MeasureTime frame
To measure and compare the time duration of analgesia in all the three groupsTimepoint: The patients will be assessed for sensory and motor block scores soon after block injection, till 30 minutes. VAS scores assessed immediately in post operative period and at regular intervals till the first onset of pain within 24 hours of block injection.—

Secondary

MeasureTime frame
To compare in all the three groups, the duration of motor block, the documentation of cumulative intra & post-operative opioid consumption and the incidence of adverse events. Timepoint: Immediately after block injection, sensory and motor block scores will be assessed for 30 min. Motor block will be assessed till regain of limb movements. For the first 24 hours after block injection if complaints of pain, then the rescue opioid will be administered and the total opioid given will be calculated. The patient will be assessed for any adverse events like post operative nausea and vomiting, weakness or paresis of the limb till the time of discharge.—

Countries

India

Contacts

Public ContactDr Yatish B

M S Ramaiah Medical College and Hospital

yatishseeni@yahoo.co.in9886197658

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026