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This is a study to establish the role of 3 biomarkers (Procalcitonin, Interleukin-6 and sTREM-1) for supporting the diagnosis and prognosis(outcome) in infection (sepsis) in critically ill patients

Serum Procalcitonin, Interleukin-6 and sTREM- 1 as diagnostic and prognostic markers in sepsis in critically ill patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/12/016503
Enrollment
30
Registered
2018-12-03
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: A00-B99- Certain infectious and parasitic diseases

Interventions

None listed

Sponsors

Self
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients 18 years of age or older admitted in various intensive care units (ICUs) of All India Institute of Medical Sciences from July 2017 to June 2019 who fulfil the definition of sepsis or SIRS will be enrolled for the study. Patients who develop new onset sepsis or septic shock in ICU will also be included in the study

Exclusion criteria

Exclusion criteria: Patients who received treatment with Corticosteroids or immunomodulators in previous 6 months Patients with malignancy, immunodeficiency or organ transplant recipients

Design outcomes

Primary

MeasureTime frame
To compare the role of Serum Procalcitonin, Interleukin-6 and sTREM-1 levels in differentiating patients with sepsis from patients with non-infectious systemic inflammatory response syndrome (NI-SIRS)Timepoint: Day 1 to Day 3—

Secondary

MeasureTime frame
To establish the role of Serum Procalcitonin, IL-6 and sTREM-1 levels in prognosis in patients with sepsisTimepoint: Day of admission to ICU to discharge or death of the patient—

Countries

India

Contacts

Public ContactAli Imran

AIIMS New Delhi

dilipshende@gmail.com8800377697

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026