FindTrial
Sign In

Study to assess role of mitomycin c to improve outcome in patients of biliary atresia after portoenterostomy surgery.

Effect of Postoperative Local Instillation of Mitomycin C at Portal Plate after Kasai Porto-Enterostomy in Patients of Extra Hepatic Biliary-Atresia: A Randomized Control Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/12/016495
Enrollment
50
Registered
2018-12-03
Start date
Unknown
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Q442- Atresia of bile ducts

Interventions

Intervention1: Mitomycin c local instillation at portal plate after surgery ( kasai portoenterostomy): Local instillation of 2 ml of Mitomycin c ( 0.5 mg/ml) after surgery. Total 3 doses. On postop

Sponsors

PGIMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Diagnosed as EXtra hepatic BIliary atresia

Exclusion criteria

Exclusion criteria: refuse to give consent

Design outcomes

Primary

MeasureTime frame
-Clearance of jaundice -Native liver survival - Improvement in liver function testTimepoint: 3 months, 6 months , 1 year—

Secondary

MeasureTime frame
NilTimepoint: Nil—

Countries

India

Contacts

Public ContactDr Shailesh Solanki

Department of pediatric surgery PGIMER

drshaileshpgi@gmail.com9111129144

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026