Health Condition 1: K650- Generalized (acute) peritonitis
Conditions
Interventions
None listed
Sponsors
department of anaesthesiology
Eligibility
Inclusion criteria
Inclusion criteria: patients with perforation peritonitis as cases and patients undergoing elective laparotomy as controls
Exclusion criteria
Exclusion criteria: 1. Patients or relative’s refusal to consent for study 2. History of ICU stay in last 6 months 3. Pre-existing significant cardiac, renal and hepatic diseases 4. Intraoperative massive blood loss or massive transfusion 5. History of CAD, CVA, malignancy, diabetes, hypertension, metabolic syndrome, PVD.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess if pre-op and post op brachial artery reactivity (Flow mediated dilation and Hyperemic velocity) can predict in-hospital mortality in perforation peritonitis patients undergoing emergency laparotomy.Timepoint: brachial artery reactivity measured preoperatively, immediated postoperatively, 24 and 48hrs postoperatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hospital length of stay b) acute kidney injury and requirement of renal replacement therapy, c) vasopressor requirement (number of days on vasopressor) d) mechanical ventilation requirement (number of days on mechanical ventilation) e) And to assess whether change in brachial artery reactivity correlates with lactate clearance in perforation peritonitis patients undergoing emergency laparotomy.Timepoint: patient will be followed up daily till 28 days or discharge or death whichever is earlier to record the above parametres | — |
Countries
India
Contacts
Public ContactHRRajathadri
AIIMS, NewDelhi
Outcome results
None listed