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Analysis of effects of atorvastatin vs rosuvastatin in causing changes in glucose metabolism and brain functions in patients taking these drugs.

An observational analysis of effect of rosuvastatin vs atorvastatin on glucose metabolism and cognitive function in dyslipidemic patients in medicine department S.N.M.C Agra.

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/11/016452
Enrollment
100
Registered
2018-11-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E782- Mixed hyperlipidemia

Interventions

Intervention1: nil: nil

Sponsors

Nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: diagnosed cases of dyslipidemia on atorvastatin or rosuvastatin therapy in all doses prescribed by the clinician

Exclusion criteria

Exclusion criteria: patients in whom an additional statin therapy could be detrimental or additive for adverse effects like myopathy and raised liver enzymes were excluded. such categories include:- • Patients with h/o liver disease or hepatic failure. • Pregnant and lactating women. • Patients with h/o serious or hypersensitivity reactions to statins. • Patients with documented h/o coronary artery disease or other atherosclerotic disease. • Patients of familial hypercholesterolemia. • Patients taking other class of hypolipidemic drugs (fibrates, niacin) and taking other cardiac drugs like Verapamil and Amiodarone • Patients taking Immunosupressants, Azole antifungal agents, Protease inhibitors.

Design outcomes

Primary

MeasureTime frame
changes in glucose metabolism by assessing HbA1c/fasting values in both groupsTimepoint: O 3 6 MONTHS

Secondary

MeasureTime frame
Changes in cognitive state by asessing MMSE values in both groupsTimepoint: 0 3 6 months

Countries

India

Contacts

Public ContactDr Shruti Sharma

SNMC, AGRA

drshruti1591@gmail.com8192072715

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026