Health Condition 1: M05- Rheumatoid arthritis with rheumatoid factor
Conditions
Interventions
None listed
Sponsors
Maulana Azad Medical College
Dr Sumeet Singla
Eligibility
Inclusion criteria
Inclusion criteria: All adult patients with Rheumatoid Arthritis (RA), as defined by the 2010 ACR/EULAR classification criteria, will be eligible for the study. Healthy volunteers among the hospital staff will also be recruited to define normal salivary IgA Anti-CCP levels in healthy population. They will include volunteers with good orodental hygiene.
Exclusion criteria
Exclusion criteria: Exclusion criteria for Healthy Volunteers: No first degree relatives with RA, no tobacco use and no past history of connective tissue disorders. Exclusion criteria for RA patients: Subjects with a history of smoking/current smokers/oral tobacco use ,with poor orodental hygiene,RA patients with coexisting connective tissue disorders like psoriatic arthritis ,Systemic Lupus Erythematosus (SLE),Primary Sjögrenâ??s Syndrome,with a history of pulmonary tuberculosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IgA Anti CCP antibodies in salivaTimepoint: At the time of recruitment into study | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation of salivary IgA Anti CCP antibodies with Serum IgG Anti CCP antibodies Timepoint: At the time of recruitment into study;Correlation of Salivary IgA Anti CCP antibody with disease activity of Rheumatoid ArthritisTimepoint: At the time of recruitment into study | — |
Countries
India
Contacts
Public ContactDr Sumeet Singla
Maulana Azad Medical College
Outcome results
None listed