Health Condition 1: M164- Bilateral post-traumatic osteoarthritis of hip Health Condition 2: M160- Bilateral primary osteoarthritis of hip Health Condition 3: M170- Bilateral primary osteoarthritis of knee Health Condition 4: M169- Osteoarthritis of hip, unspecified Health Condition 5: M179- Osteoarthritis of knee, unspecified Health Condition 6: M174- Other bilateral secondary osteoarthritis of knee Health Condition 7: M175- Other unilateral secondary osteoarthritis of knee Health Condition 8:
Conditions
Interventions
None listed
Sponsors
AIIMS JODHPUR
Eligibility
Inclusion criteria
Inclusion criteria: Signed written informed consent 1) Subjects giving informed consent. Target population 2) Subjects undergoing either elective unilateral or same-day bilateral total knee arthroplasty and total hip arthroplasty. 3) Subject willing to undergo bilateral Doppler studies.
Exclusion criteria
Exclusion criteria: 1.Hereditary (first degree) or acquired bleeding or coagulation disorder. 2.Known or suspected history of heparin-induced thrombocytopenia. 3.Need for ongoing treatment with a parenteral or oral anticoagulant (eg, Subjects with mechanical valves, warfarin-eligible atrial fibrillation). 4.Known coagulopathy. 5.Active bleeding or at high risk for bleeding. 6.Active hepatobiliary disease. 7.Any condition, in the opinion of the investigator, for which surgery or administration of an anticoagulant was contraindicated. 8.Hypersensitivity to unfractionated heparin, low molecular weight heparin, porcine products, or iodinated contrast medium. 9.Pre-operative Deep Vein Thrombosis Detected in Doppler USG and patients with previous known / documented history of thrombogenic events like DVT and pulmonary embolism
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Treatment period: 1.Symptomatic DVT 2.Asymptomatic DVT 3.Pulmonary embolism 4.Any other Follow-up period (3 week for TKA and 6 weeks for THA) 1.Symptomatic DVT 2.Asymptomatic DVT 3.Pulmonary embolism 4.Any other Timepoint: 2 time points: Treatment period (Hospital stay period) Follow-up period (3 week for TKA and 6 weeks for THA) | — |
Secondary
| Measure | Time frame |
|---|---|
| Major bleeding events Bleeding at surgical site Adjuncted clinically relevant non-major bleeding events Minor bleeding events Wound complications Timepoint: 3 week for TKA and 6 weeks for THA | — |
Countries
India
Contacts
Public ContactKISHOR KUNAL
AIIMS, JODHPUR
Outcome results
None listed