Comparative Evaluation of Two Different Local Drug Delivery Agents Adjunct to Scaling and Root Planing in treatment of Chronic Periodontitis in Type 2 Diabetes Mellitus Patients â?? A Clinical and Microbiological Study.

Comparative Evaluation of the Efficacy of Tetracycline Fibers and Chlorhexidine Chip as an Adjunct to Scaling and Root Planing in management of Chronic Periodontitis in Type 2 Diabetes Mellitus Patients Using N-Benzoyl-DL-Arginine-2-Naphthylamide Assay â?? A Clinical and Microbiological Study.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/11/016422

Enrollment

Registered

2018-11-26

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Tetracycline fibers: Tetracycline fibers [PeriColÂ®-TC] following scaling and root planing Control Intervention1: chlorhexidine chip: chlorhexidine chip [PerioColÂ®-CG] following scalin

Eligibility

Inclusion criteria

Inclusion criteria: 1.Type 2 diabetes mellitus with HbA1C 6.5 to 8% having chronic periodontitis according to American Academy of Periodontology (AAP) classification 1999 and at least two non-adjacent sites with probing pocket depth of >= 5 mm. 2.Subjects aged 30- 60 years. 3.Subjects willing to participate in the study and maintain regular appointments.

Exclusion criteria

Exclusion criteria: 1.Subjects prone to or with a history of allergic reactions to tetracycline or chlorhexidine. 2.Subjects who have received any form of periodontal therapy, surgical or non- surgical within past 6 months. 3.Subjects with aggressive periodontitis. 4.Subjects who have received antibiotic therapy within past 6months 5.Subjects on anti-inflammatory drug regimen since past 6months. 6.Subjects using mouth rinses. 7.Presence of pulpal or periapical involvement on qualifying teeth. 8.Poor, questionable or hopeless prognosis of qualifying teeth. 9.Subjects who have received orthodontic treatment in past 6months. 10.Pregnant and lactating women. 11.Physically and mentally challenged subjects. 12.Subjects using any other antimicrobial agents as adjunct for home care.

Design outcomes

Primary

Measure	Time frame
clinical parameters including bleeding on probing, gingival index, probing pocket depth, relative attachment levelTimepoint: baseline 12 weeks	—

Secondary

Measure	Time frame
Microbiological parameter assessed using BANATimepoint: baseline 12 weeks	—

Countries

India

Contacts

Public ContactDr Ashvini Padhye

MGM dental college and hospital, kamothe, navi mumbai

drashvini16@gmail.com9820138480

Outcome results