Skip to content

Herbal mouthwash for bleeding gums and plaque control

A study validating the efficacy of a herbal mouthwash in reduction of plaque and gingivitis: An in vitro evaluation and a randomized controlled clinical trial - HMW in GI

Status
Active, not recruiting
Phases
Phase 1Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/11/016395
Enrollment
120
Registered
2018-11-20
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B998- Other infectious disease

Interventions

Intervention1: Herbal mouthwashes: Subjects will be given the herbal mouthwash and asked to rinse for 2 min and expectorate. Subsequent to baseline estimation (set 1), each participant will undergo tw

Sponsors

National innovation Foundation
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: After taking a detailed medical history and initial clinical and radiologic examination, systemically healthy individuals of an age range of 18-40 years with previously untreated gingivitis and greater than or equal to 20 teeth with no visible signs of untreated dental caries will be selected. Clinical parameters for inclusion will be: 1) gingival index (GI) greater than 1; 2) probing depth less than equal to 3 mm; 3) clinical attachment loss should be 0, with no evidence of radiographic bone loss. Absence of bone loss will be considered when the distance between cemento-enamel junction and crestal bone is less than equal to 1 mm.

Exclusion criteria

Exclusion criteria: 1) Use of antibiotics and anti-inflammatory drugs in previous 6 months; 2) individuals with orthodontic appliances or prosthetic appliances that would interfere with evaluation and plaque control; 3) allergy to any ingredient used in the study; 4) alcoholics; 5) smokers or users of tobacco in any form; 6) individuals with mental retardation or medical illness; 7) Use of mouthwashes and vitamin supplements in last 3 months; 8)History of any periodontal therapy in last months; and 7) pregnant or lactating females

Design outcomes

Primary

MeasureTime frame
Improvement of gingival and plaque indicesTimepoint: Baseline, 1 week, 1 month, 2 months

Secondary

MeasureTime frame
Microbial count.Timepoint: Baseline-7 days-30 days-60 days;Patient acceptance (irritation of taste, subjective tooth staining)Timepoint: 60 days

Countries

India

Contacts

Public ContactO P Kharbanda

All India Institute of Medical Sciences

opk15@hotmail.com9899062144

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026