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To check and relate blood and Salivary protein levels among smokers with gum disease

To assess and correlate Mean Platelet Volume and Salivary C-Reactive Protein levels among smokers with chronic periodontitis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/11/016383
Enrollment
100
Registered
2018-11-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

Kunchok Dolma J
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Smokers who smoke 8 cigarettes per day for at least 3 years. Non smokers are those who has never smoked. Patients with chronic periodontitis, defined as attachment loss of atleast 4 mm at one or more sites One or more interproximal sites with pocket depth (PD) > 5mm. Minimum of 20 teeth present.

Exclusion criteria

Exclusion criteria: Ex smokers. Pregnancy, lactation, pathologies such as diabetes mellitus, hypertension, asthma, epilepsy, and coronary artery disease, skin or chronic diseases which can also increase the CRP levels. Any oral inflammatory lesions such as ulcers, desquamative lesions. History of periodontal therapy or antimicrobial therapy within 6 months. History of orthodontic therapy. Any medications known to affect periodontium like aspirin, NSAIDS. Subjects with history of coagulation disorders, chronic renal disease, peripheral vascular disease. Any infectious or debilitating disease. Habits such as tobacco chewing, alcohol intake. Patients on radiotherapy.

Design outcomes

Primary

MeasureTime frame
MPV in serum Salivary CRPTimepoint: Baseline

Secondary

MeasureTime frame
Plaque Index Gingival Index Probing depth Clinical attachment loss Timepoint: Baseline

Countries

India

Contacts

Public ContactKunchok Dolma J

JSS Dental College and Hospital

sheelagujjari@gmail.com9448836777

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026