To check the effect of guava leaf gel as local drug delivery in addition to teeth cleaning in the treatment of gum disease.

Evaluation of Psidium guajava local drug delivery as an adjunct to scaling and root planing in the treatment of chronic periodontitis: A Clinical and Microbiological Study.

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/11/016377

Enrollment

Registered

2018-11-16

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Psidium guajava gel: A gel prepared using commercially available Psidium guajava leaf extract. 0.1 to 0.2ml of the gel will be delivered once after root planing. Control Intervention1:

Eligibility

Inclusion criteria

Inclusion criteria: 1. Generalised chronic periodontitis with >=20 remaining teeth. 2. Probing pocket depth >=5mm 3. Radiographic evidence of bone loss and an evident clinical attachment loss. 4. Consenting patients who are co-operative and able to come for regular follow up.

Exclusion criteria

Exclusion criteria: 1. Pregnant/lactating women. 2. Patients who are on antibiotic therapy in the previous 6 months. 3. Patients who have undertaken any periodontal therapy in past 6 months. 4. Smoking. 5. Alcoholism.

Design outcomes

Primary

Measure	Time frame
To evaluate changes in Probing Depth and Clinical Attachment Level.Timepoint: 1, 3 months	—

Secondary

Measure	Time frame
To evaluate changes in microbial colony counts.Timepoint: 1 month	—

Countries

India

Contacts

Public ContactManohar Sharma H

JSS Dental College and Hospital

deepikamysore@yahoo.co.uk9902066073

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026