A study of the effect of Acacia nilotica (Kikar) bark extract gel on a bacterium involved in gum disease

Insilico, invitro and invivo evaluation of antibacterial activity of Terminalia chebula(R), Acacia catechu(L), Acacia nilotica(L)and Mimusops elengi(L) on Porphromonas gingivalis strains

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/11/016370

Enrollment

120

Registered

2018-11-16

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Acacia nilotica gel: 0.100 ml of acacia nilotica gel would be applied for once into the gingival sulcus after scaling, root planning and currettage. Perio pack will be placed at the sit

Eligibility

Inclusion criteria

Inclusion criteria: .Subjects residing in and around Belagavi city in an age group of 35 - 55yrs. .Patients who have not undergone any non surgical/surgical therapy in the last six months. .Willing to provide informed consent and ensuring their compliance throughout the study

Exclusion criteria

Exclusion criteria: . Subjects with history of any kind of antibiotics from past six months. . Smokers and tobacco chewers in any form. . Pregnancy and lactation. . Subjects with any kind of systemic disorders. . Subjects with periapical infection.

Design outcomes

Primary

Measure	Time frame
bleeding on probing, pocket probing depth and clinical loss of attachmentTimepoint: baseline and at the end of 6 months	—

Secondary

Measure	Time frame
Microbial count of Porphromonas gingivalisTimepoint: Baseline and at the end of 6 weeks	—

Countries

India

Contacts

Public ContactDr Shaila Kothiwale

KLE Dr Prabhakar Kore Basic Science Research Centre

drshabana_shaikh@yahoo.co.in9743155407

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026