Comparison of central lines in preventing infections in preterm infants

Comparison of UVC with PICC line insertion as a primary central line for reducing late onset sepsis in preterm infants with birth weight less than 1250grams: A randomised control trail

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/11/016329

Enrollment

338

Registered

2018-11-14

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P369- Bacterial sepsis of newborn, unspecified

Interventions

Intervention1: Peripherally Inserted Central Line: A PICC line would be inserted in the upper limb or lower limb ensuring the tip is at the junction of SVC and Right atrium or in the IVC Control Inter

Eligibility

Inclusion criteria

Inclusion criteria: All preterm infants with birth weight <1250grams and eligible for a central line placement

Exclusion criteria

Exclusion criteria: Those with major malformations, maternal chorioamnionits

Design outcomes

Primary

Measure	Time frame
Late Onset SepsisTimepoint: 48 hours from insertion to 48 hours after removal of Central line	—

Secondary

Measure	Time frame
Malposition of lIne,Thrombophlebilits, Local Infections, bleeding at site insertion, failure rates, survival, DIC, probable sepsis, Thrombus formationTimepoint: till discharge of the neonate from the unit	—

Countries

India

Contacts

Public ContactSRINIVAS MURKI

Fernandez Hospital

srinivasmurki2001@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026