Health Condition 1: H654- Other chronic nonsuppurative otitis media
Conditions
Interventions
Intervention1: Group G : Gabapentin: Subjects will receive tab 300mg gabapentin per orally 1 hour with sips of water before the induction of anesthesia in the preoperative room.
Control Intervention
Sponsors
Dr Usha R Sastry
Eligibility
Inclusion criteria
Inclusion criteria: a) Subjects in the age group of 18-59 years b) Either sex c) ASA I-II patients undergoing middle ear surgery under general anesthesia
Exclusion criteria
Exclusion criteria: a) Patient refusal b) Pregnant and lactating mothers c) Patients with history of motion sickness d) Patients with central nervous system disorders especially with cerebellar problems e) Patients with complicated chronic suppurative otitis media (CSOM)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the incidence and severity of PONV between two groups : Gabapentin versus combination of Dexamethasone - Ondansetron in middle ear surgery Timepoint: Early PONV at 0 min, 15 min, 30 min, 1 hr, 2 hr Late PONV at 4 hr, 6hr, 12hr, 18hr and 24hr. | — |
Secondary
| Measure | Time frame |
|---|---|
| Analgesic requirementTimepoint: Postoperative pain scores according to Visual Analogue scale (VAS) scales at 0 min 15 min 30 min 1 hr 2 hr 4 hr 6hr 12hr 18hr and 24hr.;Sedation score in the postoperative periodTimepoint: Incidence of postoperative sedation according to Ramsay sedation scale ;To compare the duration of antiemetic effect of drugsTimepoint: From the immediate postoperative period to the first time of occurrence of PONV. | — |
Countries
India
Contacts
Public ContactDr Manjula Devi M
St Johns medical college and Hospital
Outcome results
None listed