Health Condition 1: A419- Sepsis, unspecified organism
Conditions
Interventions
None listed
Sponsors
Prof Dr Chiranjay Mukhopadhyay
Eligibility
Inclusion criteria
Inclusion criteria: All patients aged 18 years and over in the intensive care units of Kasturba Hospital, Manipal
Exclusion criteria
Exclusion criteria: Age less than 18 years Pregnant or breast-feeding women Patients with a withdrawal of care decision at time of inclusion Patients whose anticipated duration of hospitalisation in ICU is estimated less than 48 hours Extra-corporeal circulation in the month preeceding inclusion in the case of cardiac surgery Patient with restricted liberty or under legal protection Expected lifespan less than 3 months due to pre-existing co-morbidities Blood transfusion greater than 4 units in past week Second admission to ICU or previous enrolment in study (within same hospital admission) Transfer from other hospital ICU
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Genomic/transcriptomic landscape of individual host-pathogen response and outcomes in sepsis from a lower-middle income country (LMIC). Gut microbiome alterations in correlation to sepsis endotypes and associated post sepsis mortality/re-admission.Timepoint: Four time points from admission to 6 months follow-up. | — |
Secondary
| Measure | Time frame |
|---|---|
| Cohort study of late sepsis mortality and re-admissions in LMIC (India)Timepoint: Upto 6 months follow-up post ICU discharge. | — |
Countries
India
Contacts
Public ContactChiranjay Mukhopadhyay
Kasturba Medical College Hospital, Manipal Academy of Higher Education
Outcome results
None listed