Efficacy of Dexmedetomidine on inhalational anesthetic requirement during General Anesthesia

Efficacy of Dexmedetomidine Premedication on Sevoflurane requirement during General Anesthesia in Elective Laparoscopic Cholecystectomy Surgeries: A Randomized Double-Blind Control study.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/10/016205

Enrollment

Registered

2018-10-30

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis Health Condition 2: K802- Calculus of gallbladder without cholecystitis Health Condition 3: K811- Chronic cholecystitis

Interventions

Intervention1: Dexmedetomidine: Dexmedetomidine 1 mcg/kg in 100 ml NS 15 minutes before induction of General Anesthesia Control Intervention1: Normal Saline: 100 ml Normal Saline 15 minutes before ind

Eligibility

Inclusion criteria

Inclusion criteria: All adult patients (greater than or equal to 18 years) of American Society of Anesthesiologists (ASA) Grade I and II undergoing elective laparoscopic cholecystectomy

Exclusion criteria

Exclusion criteria: 1. Patients who are allergic to the Dexmedetomidine. 2. All pregnant patients undergoing laparoscopic cholecystectomy.

Design outcomes

Primary

Measure	Time frame
To evaluate the efficacy of Dexmedetomidine pre-medication on Sevoflurane requirement in elective laparoscopic cholecystectomy surgeriesTimepoint: 1 year	—

Secondary

Measure	Time frame
To assess the hemodynamic stability intra-operatively after Dexmedetomidine pre-medication in elective laparoscopic cholecystectomy surgeries.Timepoint: 1 year	—

Countries

India

Contacts

Public ContactBRILLY JOSE

Nazareth Hospital

himjyotidas@rediffmail.com9862018017

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026