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Comparing two techniques of regional block for pain relief after breast cancer surgery

Comparison of pre-incisional Ultrasound guided PECS block and intra-operative PECS block under direct vision for postoperative pain relief,operating surgical conditions, opioid requirements and PONV in patients undergoing modified radical mastectomy:a randomized controlled trial - PVSIOPECS

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/10/016187
Enrollment
60
Registered
2018-10-29
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C50- Malignant neoplasm of breast Health Condition 2: C50-C50- Malignant neoplasms of breast

Interventions

Intervention1: Preincisional PECS block: Ultrasound guided PECS block given with 20ml 0.25% bupivacaine after endotracheal intubation but before surgical incision Control Intervention1: Intraoperative

Sponsors

Dr Shagun Bhatia Shah
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Weight 40-80 kg ASA physical status I&II Patients undergoing elective Modified Radical Mastectomy for breast cancer

Exclusion criteria

Exclusion criteria: Patient refusal Local anaesthetic allergy Infection at the site of PECS block Tumour at the site of PECS block

Design outcomes

Primary

MeasureTime frame
Postoperative VAS Scores at various time pointsTimepoint: Immediately after reversal of anaesthesia,one hour, two hours, four hours,eight hours and twenty four hours post surgery

Secondary

MeasureTime frame
Postoperative nausea and vomiting(PONV)Timepoint: Immediately after reversal of GA 1 Hour postoperatively 2 hourspostoperatively 4 hours postoperatively 8 hours post operatively 24 hours post operatively;Time to discharge from surgical intensive care unit(SICU)Timepoint: At the time of discharge from SICU;Intraoperative sevoflurane consumption/uptakeTimepoint: At the end of surgery;Intraoperative dexmedetomidine consumptionTimepoint: At the end of surgery;Intraoperative ketamine requirementTimepoint: At the end of surgery;Intraoperative propofol requirementTimepoint: At the end of surgery;Surgeon satisfaction with operating conditionsTimepoint: At the end of surgery;Intraoperative rescue fentanyl requirementTimepoint: At the end of surgery;Chronic painTimepoint: Three months post surgery

Countries

India

Contacts

Public ContactDr Shagun Bhatia Shah

Rajiv Gandhi Cancer Institute and Research Centre

drshagun_2010@rediffmail.com09891769779

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026