Health Condition 1: M267- Dental alveolar anomalies
Conditions
Interventions
Intervention1: Pregabalin: Pregabalin 75 mg single dose 1 hour post surgery add on with aceclofenac 100mg BD for three days.
Intervention2: pregabalin: Pregabalin 150 mg single dose 1 hour post surger
Sponsors
All India Institute of Medical Sciences AIIMS
Eligibility
Inclusion criteria
Inclusion criteria: Patient age between 18 to 50 years Impacted third molar teeth (grade 2nd& 3rd according to Parantâ??s classification) scheduled for surgical removal under local anesthesia will be included in the study. Patient literate enough and willing to adhere to requirement of the study procedure.
Exclusion criteria
Exclusion criteria: Patients with h/o chronic renal failure (Serum creatinine > 3mg% or patient on hemodialysis)., Pregnancy or breastfeeding, Allergy to the study medication or related drugs, Patients with h/o HIV or hepatitis B or hepatitis C infection. Patients with h/o Psychological disorder, Epilepsy, ï?¼ Receipt of medication with analgesic or anti-inflammatory properties in past 24 h before the surgery, Preoperative inflammation and pain at the surgical site and clinical or radiographic evidence of active oral disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the efficacy of add-on oral pregabalin (75 mg single dose) with Aceclofenac (100 mg) vs. add-on oral pregabalin (150 mg single dose) with Aceclofenac (100 mg) vs.Aceclofenac (100 mg) alone in post-operative after 3rd molar surgeryTimepoint: From baseline to seven days | — |
Secondary
| Measure | Time frame |
|---|---|
| To count the number of rescue medication required in each group for adequate pain control To evaluate the incidence of drug related adverse events in all groups. Timepoint: From baseline to seven days | — |
Countries
India
Contacts
Public ContactRavi Prakash Sharma
AIIMS RESIDENTIAL COMPLEX
Outcome results
None listed