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study efficacy of simple procedures like syringing and probing with mitomycin and silicone tube for nasolacrimal duct obstruction

Evaluation of efficacy of silicone intubation after probing with adjunctive mitomycin-c in adults with primary acquired nasolacrimal duct obstruction.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/10/016136
Enrollment
40
Registered
2018-10-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: case group: syringing and probing with mitomycin will be done followed by silicone intubation in patients in the case group. 0.4mg/ml mitomycin c will be injected with a 23 gauge silico

Sponsors

DR NIMMY RAJ
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with history of primary epiphora with nasolacrimal duct obstruction. 2.History less than 1 year 3.age more than 18 years, either sex 4.patients willing for procedure.

Exclusion criteria

Exclusion criteria: 1. Prior failed DCR surgery. 2.Intranasal pathologies. 3.History of trauma in nasolacrimal duct area 4.History of allergy, bleeding disorders 5.patients with ocular motility disorders

Design outcomes

Primary

MeasureTime frame
Reduction in epiphora Nasolacrimal duct patencyTimepoint: 4 1/2 months—

Secondary

MeasureTime frame
side effects of mitomycin on ocular surface and systemicTimepoint: 6 months—

Countries

India

Contacts

Public Contactprof Mandeep S Bajaj

Dr RP Centre for ophthalmic sciences AIIMS

nimmyraj19@gmail.com9910671573

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026