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Herbal Medicaments in Endodontics

A Randomized Clinical Comparative Evaluation Of Inter-Appointment Flare Ups On Placing Azadirachta Indica (Neem), Garlic (Allium Sativum L), Triphala And Calcium Hydroxide As Intra Canal Medicament, Using Verbal Rating Scale (Vrs) In A Patient With Primary Endodontic Lesion

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/10/016135
Enrollment
240
Registered
2018-10-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K044- Acute apical periodontitis of pulpal origin Health Condition 2: K044- Acute apical periodontitis of pulpal origin

Interventions

Intervention1: Azadirachtha Indica (Neem): Medicament procured from a ISO certified Ayurvedic Pharmacy to be used as intracanal medicament Intervention2: Garlic (Allium Sativum): Medicament procured f

Sponsors

Kishan K V
Lead Sponsor
Sumandeep Vidyapeeth
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: a) Healthy individuals without any medical history requiring root canal treatment. b) Age from 18 to 65 years. c) All teeth are included (single and multi rooted) with complete root formation. d) Necrosed teeth with primary endodontic lesion size e) Patient who give consent for the treatment.

Exclusion criteria

Exclusion criteria: a) Tooth with Root fractures/ resorptions, b) Tooth with Open apex( more than ISO size 80), c) Presence of Intraoral and extraoral swelling, d) Presence of Sinus opening e) Teeth requiring retreatment and previously accessed teeth. f) Tooth with large periapical lesion g) Tooth with primary perio and secondary endodontic lesions h) Patients with the history of antibiotic consumption within past one month, history of analgesic intake within past 24 hours. i) Diabetic, immune-compromised patients will be excluded.

Design outcomes

Primary

MeasureTime frame
Results of the study will help us to know that which intracanal medicament is performing better with respect to inter appointment flare up. Use of Herbal products as intracanal medicaments also will be evaluated which will benefit to overcome the antibiotic resistance.Timepoint: 1,3,7 and 14 days

Secondary

MeasureTime frame
Which intracanal medicament is performing for better Healing of the periapical lesion.Timepoint: 1,3,7 and 14 days

Countries

India

Contacts

Public ContactKishan K V

K M Shah Dental College and Hospital

drkishankv@yahoo.co.in8141787335

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026