a clinical trial comparing the effectiveness of two mouthrinses to treat gum diseases in patients undergoing fixed orthodontic treament

A Randomized Controlled trial to evaluate the Effectiveness of freshly prepared Synbiotic Mouthwash vs freshly prepared Probiotic Mouthwash as an Adjunct to Scaling in Patients with Plaque induced gingivitis along with Fixed Orthodontic Appliancesâ??

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/10/016100

Enrollment

Registered

2018-10-22

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R68- Other general symptoms and signs Health Condition 2: R688- Other general symptoms and signs

Interventions

Intervention1: synbiotic mouthrinse 10 ml twicwdaily for 30 days: fertilizer to probiotic Control Intervention1: probiotic mouthrinse 10 ml twicwdaily for 30 days: good bacteria

Eligibility

Inclusion criteria

Inclusion criteria: 1) Minimum of 20 teeth should be present in the dentition . 2) Patients with fixed orthodontic appliances 3) Patients classified as stage II and stage III gingivitis based upon the gingival score given by Loe and Silness 1964. 4)Patient with clinical bleeding on probing present. 5) Patient willing to give the informed consent and willing to comply with the study were selected

Exclusion criteria

Exclusion criteria: 1)Allergy or hypersensitivity to Chlorhexidine or related compounds. 2)Use of antibiotics within last 3 months. 3)Periodontal pockets >4mm. 4)systemic diseases. 5)Pregnancy. 6)Smoking

Design outcomes

Primary

Measure	Time frame
3. To Compare the efficacy of freshly prepared synbiotic mouthrinse and freshly prepared probiotic mouthrise on plaque induced gingivitis in patient with fixed orthodontic appliancesTimepoint: baseline, 1month.	—

Secondary

Measure	Time frame
1. To Compare the efficacy of Chlorhexidine mouthrinse(0.12%) and freshly prepared probiotic mouthrise on plaque induced gingivitis in patient with fixed orthodontic appliances 2. To Compare the efficacy of Chlorhexidine mouthrinse(0.12%) and freshly prepared Synbiotic mouthrise on plaque induced gingivitis in patient with fixed orthodontic appliances patients Timepoint: baseline, 1month.;4. To Compare the efficacy of warm saline rinse and all of the above on plaque induced gingivitis in patient with fixed orthodontic appliancesTimepoint: baseline, 1month.	—

Measure

Time frame

1. To Compare the efficacy of Chlorhexidine mouthrinse(0.12%) and freshly prepared probiotic mouthrise on plaque induced gingivitis in patient with fixed orthodontic appliances 2. To Compare the efficacy of Chlorhexidine mouthrinse(0.12%) and freshly prepared Synbiotic mouthrise on plaque induced gingivitis in patient with fixed orthodontic appliances patients Timepoint: baseline, 1month.;4. To Compare the efficacy of warm saline rinse and all of the above on plaque induced gingivitis in patient with fixed orthodontic appliancesTimepoint: baseline, 1month.

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Countries

India

Contacts

Public ContactDr Nikita Patil

Nair Hospital Dental college

maladixit25@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026