Skip to content

Effect of two different drug on airway visualization and intubation

A comparison of dexmedetomidine plus ketamine combination with demedetomidine alone for awake fiberoptic nasotracheal intubation : A randomized control trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/10/016078
Enrollment
40
Registered
2018-10-18
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H958- Other intraoperative and postprocedural complications and disorders of the ear and mastoid process, not elsewhere classified Health Condition 2: J989- Respiratory disorder, unspecified

Interventions

Intervention1: Group D (intravenous dexmedetomidine): Patients will receives a loading infusion dose of dexmedetomidine 1mcg/kg over 10 minutes iv and after loading dose patient received plane norma

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age: 20 ââ?¬â?? 60 years. 2. ASA grade: I / II. 3. Mallampati grading(MPG) 1 and 2 4. Thyro mental distance(TMD) >6.5 5. Duration of surgery of more than one hour

Exclusion criteria

Exclusion criteria: 1.Uncooperative patients 2. Any type of A-V block on ECG or heart rate 3. A history of alcohol or drug abuse (e.g. Opioids ) 4. Known allergy, sensitivity, asthma, contraindications to any study drug 5. Current history of psychiatric disorder or any respiratory disorder 6. Pregnancy 7. Thrombocytopenia and coagulopathies

Design outcomes

Primary

MeasureTime frame
1. Haemodynamics stabilityTimepoint: till endotracheal intubation

Secondary

MeasureTime frame
1. Quality of sedation based on time to achieve RSS 3 2. Performer satisfaction (Fiberoptic endoscopy time, intubation time, number of attempts, Discomfort Score, endoscopy score, intubation score and Post Intubation score) 3. Level of recall 4. Adverse events 5. Patients satisfaction Timepoint: 24 hours

Countries

India

Contacts

Public ContactDr Geeta Singariya

Dr S N Medical Collage Jodhpur

geetamanojkamal@gmail.com09414803554

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026