None listed
Conditions
Interventions
Intervention1: INTERVENTION GROUP: 8-16 years children will be supplemented with oral PUFA (EPA-720mg
DHA-480mg) 2 capsules per day for 8 weeks, with high risk of externalizing disorders
Control Intervention1: PLACEBO GROUP: 8-16 years children will be supplemented with oral placebo 2 capsules per day
Sponsors
National Institute of Mental Health and Neuro Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age 8-16 years 2.Informed consent from legal guardian and assent from child.
Exclusion criteria
Exclusion criteria: 1. History of supplementation with PUFA in the last 4 months. 2. Presence of any major psychiatric disorders other than ADHD, CD, ODD (confirmed by MINI-KID) 3. Clinical history suggestive of intellectual developmental delay. 4. Presence of any chronic medical or neurological illness. 5. Presence of sensory impairment that may interfere with study related assessments; H/O known allergies to any of the molecules being used as intervention in the study; Severe malnourishment or anaemia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PUFA supplementation improves functional brain connectivityTimepoint: 8 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| PUFA blood levels correlates with cognitive assessmentsTimepoint: 8 weeks | — |
Countries
India
Contacts
Public ContactMonisha
National Institute Of Mental Health and Neurosciences
Outcome results
None listed